Mbhokhwe is survived by his wife and three children.
The 48-year-old was based at the Fire and Rescue Service Training Academy in Epping.
Divisional Commander Makosandile Mbhokhwe will be sorely missed by his colleagues.
He was a credit to the Fire and Rescue Service and was also named Officer of the Year at the 2018 Safety and Security Annual Awards - a testament to his calibre and contribution to the Service.
The City expresses its heartfelt condolences to his family and friends during this very difficult time, as well as his colleagues.
This is the first staff member that the Fire and Rescue Service has lost to COVID-19, and we hope that the department will be spared any
further loss of life,' said the City's Mayoral Committee Member for Safety and Security, Alderman JP Smith.
Normally we tend to express acknowledgement for a person posthumously.
In this case, we were indeed able to honour him with our Officer of the Year award while he was still with us - a rare privilege indeed,' said Executive Director for Safety and Security, Richard Bosman.
The Fire and Rescue Service traditionally honours fallen members with a Brigade Funeral or a Memorial Service for staff to attend.
As a result of COVID-19 protocols prohibiting large gatherings, the Service Facilitated a Guard of Honour that visited eight fire stations across the metropole this morning, to allow staff to pay their last respects.